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recombinant hhip protein  (R&D Systems)


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    Structured Review

    R&D Systems recombinant hhip protein
    Recombinant Hhip Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+hhip+protein/pm36346845-295-0-6?v=R%26D+Systems
    Average 92 stars, based on 4 article reviews
    recombinant hhip protein - by Bioz Stars, 2026-07
    92/100 stars

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    92
    R&D Systems recombinant hhip protein
    Recombinant Hhip Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+hhip+protein/pm36346845-295-0-6?v=R%26D+Systems
    Average 92 stars, based on 1 article reviews
    recombinant hhip protein - by Bioz Stars, 2026-07
    92/100 stars
      Buy from Supplier

    90
    R&D Systems hhip
    (A) IPA upstream regulator analysis of hAEC2s co-cultured with AHLM. (B) Bulk RNA-seq analysis of MRC5 and AHLM with differential gene expression analysis. (C) Treatment of hAEC2s+AHLM organoids <t>with</t> <t>BMP4</t> increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (D) BMP treatment increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (E) hAEC2s from IPF lungs demonstrates decreased SFTPC and <t>HHIP</t> expression when compared to hAEC2s from normal donors. (F) Treatment of hAEC2s+AHLM organoids with HHIP increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (G) HHIP increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (H) HHIP-treated AHLM isolated from D14 organoid culture have decreased GLI1 and increased BMP3 and BMP4 mRNA levels. (I) HHIP-treated hAEC2s+AHLM organoids at D14 show significantly higher fraction of pSMAD1/5/8+ cells. See also
    Hhip, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+hhip+protein/bio_rxiv__2020__06__06__136713-192-11-13?v=R%26D+Systems
    Average 90 stars, based on 1 article reviews
    hhip - by Bioz Stars, 2026-07
    90/100 stars
      Buy from Supplier

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    (A) IPA upstream regulator analysis of hAEC2s co-cultured with AHLM. (B) Bulk RNA-seq analysis of MRC5 and AHLM with differential gene expression analysis. (C) Treatment of hAEC2s+AHLM organoids with BMP4 increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (D) BMP treatment increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (E) hAEC2s from IPF lungs demonstrates decreased SFTPC and HHIP expression when compared to hAEC2s from normal donors. (F) Treatment of hAEC2s+AHLM organoids with HHIP increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (G) HHIP increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (H) HHIP-treated AHLM isolated from D14 organoid culture have decreased GLI1 and increased BMP3 and BMP4 mRNA levels. (I) HHIP-treated hAEC2s+AHLM organoids at D14 show significantly higher fraction of pSMAD1/5/8+ cells. See also

    Journal: bioRxiv

    Article Title: Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair

    doi: 10.1101/2020.06.06.136713

    Figure Lengend Snippet: (A) IPA upstream regulator analysis of hAEC2s co-cultured with AHLM. (B) Bulk RNA-seq analysis of MRC5 and AHLM with differential gene expression analysis. (C) Treatment of hAEC2s+AHLM organoids with BMP4 increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (D) BMP treatment increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (E) hAEC2s from IPF lungs demonstrates decreased SFTPC and HHIP expression when compared to hAEC2s from normal donors. (F) Treatment of hAEC2s+AHLM organoids with HHIP increases SFTPC and decreases KRT5 mRNA expression at D14 of culture. (G) HHIP increases SFTPC+ cells and decreases KRT5+ cells in D14 organoids. (H) HHIP-treated AHLM isolated from D14 organoid culture have decreased GLI1 and increased BMP3 and BMP4 mRNA levels. (I) HHIP-treated hAEC2s+AHLM organoids at D14 show significantly higher fraction of pSMAD1/5/8+ cells. See also

    Article Snippet: Where applicable, recombinant BMP4 (Cat#314-BP-010; R&D Systems; used 50 ng/mL) and HHIP (Cat#9280-HP-050; R&D Systems; used 5 μg/mL) were added to the media after 48 hours and replenished in every media change.

    Techniques: Cell Culture, RNA Sequencing, Gene Expression, Expressing, Isolation